Mitochondria Phenome Knowledgebase

Gene Symbol BCL2
Ensembl ID ENSG00000171791 Entrez 596
Gene Alias Bcl-2 Subcellular Locations Mitochondria Mitochondrial-outer-membrane
Map Position 18q21.33|18q21.3 Subcell PMIDs 1453000
OMIM Gene 151430 Protein Complex
Swissprot ID P10415 Swissprot Description Apoptosis regulator Bcl-2
OMIM Disease Chronic lymphocytic leukemia (CLL) [151400]

Gene-Feature associations that are associated with 1 Gene

Gene OMIM Disease Phenotypic Feature Phenotype Annotation Clinical Category PMIDs
BCL2 151400 Neoplasms oncologic #2406517 #2648153 #8220113 #11120335 #11224600 #11557789 #11699413 #12200703 #15748964
BCL2 151400 Leukemia-Lymphoma follicular; follicular lymphoma; non hodgkin lymphoma; lymphocytic leukemia oncologic 2406517 2648153 8220113 11120335 11224600 11557789 11699413 12200703 15748964
BCL2 151400 Digestive-system-diseases gastrointestinal #10733261 #11557789
BCL2 151400 Liver-diseases gastrointestinal #10733261 #11557789
BCL2 151400 Hepatomegaly gastrointestinal 10733261 11557789
BCL2 151400 Hematologic-diseases hematologic #10561025 #10733261 #11120335 #11557789 #11699413 #12200703 #15748964
BCL2 151400 Anemia hemolytic; autoimmune; refractory anemia hematologic 10561025 11699413
BCL2 151400 Blood-platelet-disorders hematologic #10561025
BCL2 151400 Thrombocytopenia autoimmune hematologic 10561025
BCL2 151400 Blood-protein-disorders hematologic #10561025 #12200703
BCL2 151400 Hypergammaglobulinemia hypergammaglobulinemia; T cell dysfunction hematologic 10561025
BCL2 151400 Hypoalbuminemia elevated lactate dehydrogenase (LDH); elevated beta2 microglobulin; serum albumin levels decreased hematologic 10561025 12200703
BCL2 151400 Bone-marrow-diseases myelodysplasia; bone marrow involvement; infiltration; bone marrow infiltration; bone marrow failure; paratrabecular nodules; bone marrow blastosis hematologic 10733261 11120335 11557789 11699413 12200703 15748964
BCL2 151400 Leukocyte-disorders hematologic #10561025
BCL2 151400 Leukopenia autoimmune hematologic 10561025
BCL2 151400 Lymphatic-diseases lymphadenopathy; adenopathy; lymph node involvement hematologic 10733261 11120335 11557789 12200703 15748964
BCL2 151400 Skin-diseases cutaneous lesions; cutaneous follicular lymphoma; extranodal lymphomas; papule; plaque; tumors; erythema dermatologic 11224600 11557789
BCL2 151400 Immune-system-diseases immunologic #10561025 #10733261
BCL2 151400 Immune-deficiency autoimmune disease; cellular immunity abnormal; humoral immunity abnormal; immune defects immunologic 10561025 10733261
BCL2 151400 Infections recurrent; opportunistic pathogens immunologic 10561025
BCL2 151400 Splenomegaly splenic involvement miscellaneous 10733261 11120335 11557789 15748964

©2006-2009 Stanford Genome Technology Center, Stanford University | Webmastercreative commons