| ALAS2 |
301300 |
Neoplasms |
|
oncologic |
#16540354 |
| ALAS2 |
301300 |
Digestive-system-neoplasms |
|
oncologic |
#16540354 |
| ALAS2 |
301300 |
Hepatocellular-carcinoma |
|
oncologic |
16540354 |
| ALAS2 |
301300 |
Digestive-system-diseases |
|
gastrointestinal |
#1570328 #7949148 #8107717 #10029606 #15477213 #16540354 |
| ALAS2 |
301300 |
Gastrointestinal-diseases |
|
gastrointestinal |
#16540354 |
| ALAS2 |
301300 |
Esophageal-varices |
episodes; variceal bleeding
|
gastrointestinal |
16540354 |
| ALAS2 |
301300 |
Liver-diseases |
|
gastrointestinal |
#7949148 #8107717 #10029606 #15477213 #16540354 |
| ALAS2 |
301300 |
Fatty-liver |
liver fatty changes
|
gastrointestinal |
10029606 |
| ALAS2 |
301300 |
Liver-cirrhosis |
Biopsy findings; precirrhotic changes; liver hemosiderin; micronodular cirrhosis
|
gastrointestinal |
10029606 16540354 |
| ALAS2 |
301300 |
Liver-enzymes-abnormal |
AST elevated; GGT elevated
|
gastrointestinal |
8107717 10029606 15477213 |
| ALAS2 |
301300 |
Hepatomegaly |
hepatosplenomegaly
|
gastrointestinal |
7949148 10029606 |
| ALAS2 |
301300 |
Vomiting |
nausea
|
gastrointestinal |
1570328 |
| ALAS2 |
301300 |
Respiratory-tract-diseases |
|
respiratory |
#7560104 #7949148 #8107717 #12663458 #15477213 |
| ALAS2 |
301300 |
Respiration-disorders |
dyspnea; breathlessness; chronic obstructive lung disease; airways disease
|
respiratory |
7560104 7949148 8107717 12663458 15477213 |
| ALAS2 |
301300 |
Nervous-system-diseases |
|
neurologic |
#12663458 |
| ALAS2 |
301300 |
Neurologic-manifestations |
|
neurologic |
#12663458 |
| ALAS2 |
301300 |
Neurobehavioral-manifestations |
|
neurologic |
#12663458 |
| ALAS2 |
301300 |
Lethargy |
tiredness
|
neurologic |
12663458 |
| ALAS2 |
301300 |
Genitourinary-diseases |
|
genitourinary |
#15477213 #16540354 |
| ALAS2 |
301300 |
Male-genital-diseases |
|
genitourinary |
#16540354 |
| ALAS2 |
301300 |
Infertility-male |
erectile dysfunction; impotence
|
genitourinary |
16540354 |
| ALAS2 |
301300 |
Female-genital-diseases |
|
genitourinary |
#15477213 |
| ALAS2 |
301300 |
Menstruation-disturbances |
amenorrhea
|
genitourinary |
15477213 |
| ALAS2 |
301300 |
Cardiovascular-diseases |
|
cardiovascular |
#1570328 #7949148 #10029606 |
| ALAS2 |
301300 |
Congenital-heart-defects |
interatrial septal defect
|
cardiovascular |
7949148 |
| ALAS2 |
301300 |
Heart-diseases |
|
cardiovascular |
#1570328 #10029606 |
| ALAS2 |
301300 |
Arrhythmia |
tachycardia
|
cardiovascular |
1570328 |
| ALAS2 |
301300 |
Cardiomyopathy |
cardiomegaly; cardiac enlargement
|
cardiovascular |
10029606 |
| ALAS2 |
301300 |
Cardiorespiratory-arrest |
died within first year
|
cardiovascular |
7949148 |
| ALAS2 |
301300 |
Vascular-diseases |
|
cardiovascular |
#7949148 |
| ALAS2 |
301300 |
Embolism-and-thrombosis |
thrombosis; deep venous thrombosis; repeated episodes; pulmonary emboli
|
cardiovascular |
7949148 |
| ALAS2 |
301300 |
Hematologic-diseases |
|
hematologic |
#1570328 #7560104 #7949148 #8107717 #10029606 #10577279 #11110715 #12031592 #12393718 #12531813 #12663458 #15477213 #16446107 #16540354 |
| ALAS2 |
301300 |
Anemia |
hypochromic; sideroblastic; microcytic; anisocytosis; poikilocytosis; bizarre echinocytes; tear drop poikilocytes
|
hematologic |
1570328 7560104 7949148 8107717 10029606 10577279 11110715 12031592 12393718 12531813 12663458 15477213 16446107 16540354 |
| ALAS2 |
301300 |
Blood-platelet-disorders |
|
hematologic |
#8107717 #12663458 |
| ALAS2 |
301300 |
Thrombocytopenia |
low platelet count
|
hematologic |
12663458 |
| ALAS2 |
301300 |
Thrombocytosis |
high platelet count
|
hematologic |
8107717 |
| ALAS2 |
301300 |
Bone-marrow-diseases |
myelodysplasia; myelofibrosis; hypercellular; hypererythroid; dyserythropoiesis; ringed sideroblasts; erythroid hyperplasia; ring sideroblasts
|
hematologic |
1570328 7560104 8107717 10029606 10577279 11110715 12031592 12393718 12531813 12663458 15477213 16446107 16540354 |
| ALAS2 |
301300 |
Hemoglobin-levels-abnormal |
hemoglobin deficiency
|
hematologic |
7560104 7949148 8107717 10029606 10577279 11110715 12031592 12393718 12531813 12663458 15477213 16446107 16540354 |
| ALAS2 |
301300 |
Skin-diseases |
|
dermatologic |
#1570328 #7560104 #10577279 #15477213 |
| ALAS2 |
301300 |
Pigmentation-disorders |
|
dermatologic |
#15477213 |
| ALAS2 |
301300 |
Hyperpigmentation |
skin hyperpigmentation
|
dermatologic |
15477213 |
| ALAS2 |
301300 |
Paleness |
pallor; pale
|
dermatologic |
1570328 7560104 10577279 |
| ALAS2 |
301300 |
Metabolic-diseases |
|
metabolic |
#1570328 #7560104 #7949148 #8107717 #10029606 #10577279 #11110715 #12031592 #12393718 #12531813 #12663458 #15477213 #16446107 #16540354 |
| ALAS2 |
301300 |
Hemochromatosis |
hemosiderosis; iron deposition; liver stainable iron
|
metabolic |
7560104 7949148 10029606 11110715 15477213 16540354 |
| ALAS2 |
301300 |
Hyperferricemia |
iron stores increased; serum ferritin elevated; iron overload; serum iron increased
|
metabolic |
1570328 7560104 7949148 8107717 10029606 10577279 11110715 12031592 12393718 12531813 12663458 15477213 16446107 16540354 |
| ALAS2 |
301300 |
Exercise-intolerance |
fatigue; shortness of breath; weakness; asthenia
|
miscellaneous |
1570328 7560104 7949148 8107717 10577279 11110715 15477213 16446107 |
| ALAS2 |
301300 |
Splenomegaly |
hepatosplenomegaly; hypersplenism
|
miscellaneous |
1570328 7949148 8107717 10029606 |
| ALAS2 |
301300 |
Alpha-fetoprotein-abnormal |
alpha fetoprotein elevated
|
miscellaneous |
16540354 |
| ALAS2 |
301300 |
Vitamin-responsive |
pyridoxine; vitamin B6
|
miscellaneous |
7560104 7949148 8107717 10029606 10577279 11110715 12031592 12393718 12531813 12663458 |
