| ACADM |
201450 |
Musculoskeletal-diseases |
|
musculoskeletal |
#7876853 #11524729 |
| ACADM |
201450 |
Muscular-diseases |
type 2 fiber predominance; lipid droplets between myofibrils; glycogen accumulation
|
musculoskeletal |
7876853 #11524729 |
| ACADM |
201450 |
Rhabdomyolysis |
acute muscle necrosis
|
musculoskeletal |
7876853 11524729 |
| ACADM |
201450 |
Myoglobinuria |
dark brown coloured urine
|
musculoskeletal |
7876853 |
| ACADM |
201450 |
Digestive-system-diseases |
|
gastrointestinal |
#2246856 #2279505 #2380628 #7876853 #7929823 #9158144 #9350306 #11346377 #11486912 #11524729 #12897989 #15858970 |
| ACADM |
201450 |
Gastrointestinal-diseases |
|
gastrointestinal |
#7929823 #9158144 |
| ACADM |
201450 |
Gastroenteritis |
viral
|
gastrointestinal |
7929823 9158144 |
| ACADM |
201450 |
Liver-diseases |
hepatic failure; hepatic coma; liver function abnormal
|
gastrointestinal |
#2246856 2279505 #2380628 #7876853 7929823 #9158144 #9350306 #11346377 11524729 #12897989 #15858970 |
| ACADM |
201450 |
Fatty-liver |
hepatic fatty infiltration; large droplet steatosis
|
gastrointestinal |
2246856 2279505 7929823 9350306 |
| ACADM |
201450 |
Liver-enzymes-abnormal |
transaminases abnormal; ALT elevated; AST elevated; GGT elevated
|
gastrointestinal |
2279505 7876853 7929823 11346377 12897989 |
| ACADM |
201450 |
Hepatomegaly |
liver enlargement
|
gastrointestinal |
2380628 9158144 15858970 |
| ACADM |
201450 |
Feeding-difficulties |
feeding rejection; fed poorly
|
gastrointestinal |
2246856 2279505 7929823 11486912 15858970 |
| ACADM |
201450 |
Diarrhea |
watery diarrhea; diarrhoea
|
gastrointestinal |
2279505 9158144 9350306 11346377 |
| ACADM |
201450 |
Vomiting |
vomiting and nausea
|
gastrointestinal |
7876853 9158144 11346377 11524729 12897989 |
| ACADM |
201450 |
Respiratory-tract-diseases |
|
respiratory |
#7929823 #9158144 #15858970 |
| ACADM |
201450 |
Lung-diseases |
|
respiratory |
#15858970 |
| ACADM |
201450 |
Pulmonary-edema |
pulmonary oedema
|
respiratory |
15858970 |
| ACADM |
201450 |
Pulmonary-hemorrhage |
|
respiratory |
15858970 |
| ACADM |
201450 |
Respiration-disorders |
apnea; respiratory status impaired
|
respiratory |
#7929823 9158144 15858970 |
| ACADM |
201450 |
Hyperventilation |
tachypnea; tachypnoeic
|
respiratory |
7929823 15858970 |
| ACADM |
201450 |
Nervous-system-diseases |
|
neurologic |
#2279505 #7876853 #7929823 #9158144 #9350306 #11263545 #11346377 #11349232 #11486912 #11524729 #12897989 #15858970 |
| ACADM |
201450 |
Central-nervous-system-diseases |
|
neurologic |
#7876853 #9158144 #9350306 #11263545 #11349232 #11524729 #12897989 |
| ACADM |
201450 |
Brain-diseases |
|
neurologic |
#7876853 #9158144 #9350306 #11263545 #11349232 #11524729 #12897989 |
| ACADM |
201450 |
Brain-edema |
cerebral edema; CT findings; thin lateral ventricles indicative of cerebral oedema; diffuse cerebral oedema
|
neurologic |
7876853 9350306 12897989 |
| ACADM |
201450 |
Encephalopathy |
acute encephalopathy
|
neurologic |
7876853 11263545 11524729 |
| ACADM |
201450 |
Seizures |
seizures; convulsions
|
neurologic |
9158144 11349232 |
| ACADM |
201450 |
Headache-disorders |
headache
|
neurologic |
7876853 12897989 |
| ACADM |
201450 |
Electroencephalogram-abnormal |
generalised slowing background pattern
|
neurologic |
7876853 |
| ACADM |
201450 |
Neurologic-manifestations |
|
neurologic |
#2279505 #7876853 #7929823 #9158144 #11263545 #11346377 #11349232 #11486912 #11524729 #12897989 #15858970 |
| ACADM |
201450 |
Neurobehavioral-manifestations |
|
neurologic |
#2279505 #7876853 #7929823 #11263545 #11346377 #11349232 #11486912 #11524729 #12897989 #15858970 |
| ACADM |
201450 |
Speech-disorders |
incoherent speech
|
neurologic |
12897989 |
| ACADM |
201450 |
Consciousness-disorders |
coma; delirious; consciousness altered; comatose
|
neurologic |
2279505 7876853 7929823 11349232 11524729 12897989 |
| ACADM |
201450 |
Developmental-delay |
cerebral palsy
|
neurologic |
7929823 11263545 |
| ACADM |
201450 |
Psychomotor-agitation |
ADHD; attention deficit; hyperactivity; agitated patient; motor restlessness
|
neurologic |
7876853 11263545 |
| ACADM |
201450 |
Irritability |
irritable
|
neurologic |
2279505 7876853 |
| ACADM |
201450 |
Lethargy |
drowsiness; lethargic; sudden onset of lethargy
|
neurologic |
7876853 11346377 11349232 11486912 12897989 15858970 |
| ACADM |
201450 |
Neuromuscular-manifestations |
|
neurologic |
#2279505 #7876853 #9158144 #11263545 #11524729 #15858970 |
| ACADM |
201450 |
Muscle-hypotonia |
hypotonic; muscle tone decreased
|
neurologic |
2279505 9158144 15858970 |
| ACADM |
201450 |
Muscle-weakness |
progressive weakness
|
neurologic |
7876853 11263545 11524729 |
| ACADM |
201450 |
Genitourinary-diseases |
|
genitourinary |
#7876853 #11346377 #12897989 |
| ACADM |
201450 |
Urologic-diseases |
|
genitourinary |
#7876853 #11346377 #12897989 |
| ACADM |
201450 |
Kidney-diseases |
|
genitourinary |
#7876853 #11346377 #12897989 |
| ACADM |
201450 |
Renal-insufficiency |
moderate renal insufficiency; acute renal failure
|
genitourinary |
7876853 12897989 |
| ACADM |
201450 |
Creatinine-levels-abnormal |
plasma creatinine elevated
|
genitourinary |
7876853 |
| ACADM |
201450 |
Uremia |
increase of plasma urea; elevated urea levels
|
genitourinary |
7876853 11346377 |
| ACADM |
201450 |
Cardiovascular-diseases |
|
cardiovascular |
#2246856 #2380628 #7876853 #7929823 #9158144 #9350306 #11263545 #11346377 #11349232 #11486912 #11524729 #12897989 #15858970 |
| ACADM |
201450 |
Heart-diseases |
|
cardiovascular |
#2380628 #7876853 #7929823 #11346377 #12897989 #15858970 |
| ACADM |
201450 |
Arrhythmia |
atrial bigeminy; heart block; arrhythmic; ventricular tachycardia; atrial fibrillations; bradycardia; ventricular fibrillation
|
cardiovascular |
11346377 12897989 15858970 |
| ACADM |
201450 |
Cardiomyopathy |
left ventricle hypertrophy; repolarisation disturbances; cardiomegaly; biventricular dilatation
|
cardiovascular |
2380628 7876853 7929823 15858970 |
| ACADM |
201450 |
Cardiorespiratory-arrest |
sudden infant death; SIDS; cardiac dysfunction; respiratory arrest; cardiac arrest; asystolic cardiac arrest
|
cardiovascular |
2246856 2380628 7929823 9158144 9350306 11263545 11349232 11486912 11524729 12897989 15858970 |
| ACADM |
201450 |
Blood-circulation-disorder |
cool extremities; blue extremities; perfusion abnormal; poor perfusion; slow capillary refill; probably dehydration related
|
cardiovascular |
11346377 |
| ACADM |
201450 |
Hematologic-diseases |
|
hematologic |
#7929823 #11346377 #15858970 |
| ACADM |
201450 |
Blood-coagulation-disorders |
prothrombin time prolonged; intravascular coagulation
|
hematologic |
7929823 15858970 |
| ACADM |
201450 |
Blood-protein-disorders |
|
hematologic |
#11346377 |
| ACADM |
201450 |
Hyperalbuminemia |
albumin levels increased
|
hematologic |
11346377 |
| ACADM |
201450 |
Hemoglobin-levels-abnormal |
hemoglobin deficiency
|
hematologic |
11346377 15858970 |
| ACADM |
201450 |
Skin-diseases |
|
dermatologic |
#7929823 #15858970 |
| ACADM |
201450 |
Paleness |
dusky pallor; pale
|
dermatologic |
7929823 15858970 |
| ACADM |
201450 |
Metabolic-diseases |
|
metabolic |
#2246856 #2279505 #2380628 #7876853 #7929823 #9158144 #9350306 #11346377 #11349232 #11409868 #11486912 #11524729 #12897989 #15858970 |
| ACADM |
201450 |
Acid-base-imbalance |
|
metabolic |
#2279505 #7876853 #11349232 #11486912 #12897989 #15858970 |
| ACADM |
201450 |
Acidosis |
mild; lactate acidosis; metabolic acidosis
|
metabolic |
2279505 7876853 12897989 15858970 |
| ACADM |
201450 |
Hypoketosis |
hypoketotic hypoglycemia
|
metabolic |
11349232 11486912 |
| ACADM |
201450 |
Metabolic-brain-diseases |
CSF protein elevated
|
metabolic |
#2246856 #2279505 7876853 #7929823 #9158144 #9350306 |
| ACADM |
201450 |
Reye-like-symptoms |
reye syndrome like
|
metabolic |
2246856 2279505 7929823 9158144 9350306 |
| ACADM |
201450 |
Glucose-metabolism-disorders |
|
metabolic |
#2246856 #2279505 #2380628 #7929823 #11346377 #11349232 #11486912 #12897989 |
| ACADM |
201450 |
Hypoglycemia |
hypoglycemic shock; hypoglycaemia
|
metabolic |
2246856 2279505 2380628 7929823 11346377 11349232 11486912 12897989 |
| ACADM |
201450 |
Hyperammonemia |
ammonia levels elevated
|
metabolic |
11346377 12897989 |
| ACADM |
201450 |
Aminoacid-levels-abnormal |
elevated alanine
|
metabolic |
11346377 |
| ACADM |
201450 |
Phosphorus-metabolism-disorders |
|
metabolic |
#7876853 |
| ACADM |
201450 |
Hyperphosphatemia |
phosphate concentrations increased
|
metabolic |
7876853 |
| ACADM |
201450 |
Water-electrolyte-imbalance |
|
metabolic |
#7876853 #11346377 #11524729 #12897989 |
| ACADM |
201450 |
Dehydration |
|
metabolic |
11346377 11524729 |
| ACADM |
201450 |
Hyperkalemia |
potassium concentration elevated
|
metabolic |
7876853 12897989 |
| ACADM |
201450 |
Hypocalcemia |
calcium levels abnormal
|
metabolic |
11346377 |
| ACADM |
201450 |
Acylcarnitine-profile-abnormal |
elevated medium chain acylcarnitines; elevated C6:0 C8:0 C8:1 C10:1 acylcarnitines; octanoylcarnitine elevated
|
metabolic |
2246856 2279505 7876853 11349232 11409868 11486912 12897989 15858970 |
| ACADM |
201450 |
Acylglycine-profile-abnormal |
superylglycinuria; hexanoylglycinuria; phenylpropionylglycinuria; urinary excretion of glycine esters
|
metabolic |
2246856 2380628 7876853 11349232 11409868 11486912 12897989 15858970 |
| ACADM |
201450 |
Carnitine-levels-abnormal |
decreased total carnitine; decreased free carnitine; elevated esterified carnitine; urinary excretion of carnitine
|
metabolic |
2279505 2380628 7876853 11486912 15858970 |
| ACADM |
201450 |
Fatty-acids-abnormal |
octanoic acid elevated; plasma
|
metabolic |
11486912 |
| ACADM |
201450 |
Organic-acids-abnormal |
dicarboxylic aciduria; adipic aciduria; suberic aciduria; sebacic aciduria; decanoic aciduria; elevated octanoylcarnitine; suberylglycinuria
|
metabolic |
2246856 #2279505 2380628 7876853 7929823 #11349232 #11409868 #12897989 #15858970 |
| ACADM |
201450 |
Dicarboxylic-aciduria |
dicarboxylic acids elevated; medium chain dicarboxylic aciduria
|
metabolic |
2246856 2279505 2380628 7929823 11349232 11409868 12897989 15858970 |
| ACADM |
201450 |
Immune-system-diseases |
|
immunologic |
#2246856 #2279505 #2380628 #11346377 #11486912 #11524729 |
| ACADM |
201450 |
Infections |
intercurrent; viral infections; respiratory tract infections; rotavirus; respiratory syncytial virus; recurrent infections
|
immunologic |
2246856 2279505 2380628 11346377 11486912 11524729 |
| ACADM |
201450 |
Body-temperature-changes |
|
miscellaneous |
#2279505 #9158144 #9350306 #11524729 #15858970 |
| ACADM |
201450 |
Fever |
|
miscellaneous |
2279505 9158144 9350306 11524729 |
| ACADM |
201450 |
Hypothermia |
hypothermic
|
miscellaneous |
15858970 |
| ACADM |
201450 |
Growth-disorders |
|
miscellaneous |
#11263545 |
| ACADM |
201450 |
Failure-to-thrive |
|
miscellaneous |
11263545 |
| ACADM |
201450 |
Mitochondria-abnormal |
elongated; abnormally configurated; increased numbers; matrix density increased; cristae widening
|
miscellaneous |
2279505 |
| ACADM |
201450 |
Creatine-kinase-abnormal |
elevated
|
miscellaneous |
7876853 11346377 12897989 |
